Research is showing that vitamin K can help to regulate your glucose metabolism.  This may be because the vitamin converts to a substance called carboxylated osteocalcin in your body, which affects insulin sensitivity.

A recent study found that that vitamin K2 supplementation increased insulin sensitivity in healthy young men.  The effect seemed to be related to increased carboxylated osteocalcin levels, rather than to another factor such as modulation of inflammation.

According to the study in Diabetes Care:

“Our results are consistent with previous studies that demonstrated improved glucose intolerance or relieved insulin resistance by treatment with vitamin K1 or vitamin K2 … Although our study could not provide the underlying mechanism, we speculate that [carboxylated osteocalcin] or vitamin K could modulate adipokines or inflammatory pathways other than the IL-6 pathways. Alternatively, [carboxylated osteocalcin] can directly regulate glucose disposal at skeletal muscle or adipose tissues.”


Diabetes Care September 2011; 34(9); e147

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